Pathogenesis of Human Pulmonary Tuberculosis: Insights from the Rabbit Model

Examines the pathogenesis of human pulmonary tuberculosis in all of its stages, with a primary focus on the rabbit model.
• Reviews the interplay of delayed-type hypersensitivity and cell-mediated immunity, clearly showing how both are needed to control the growth of the tubercle bacillus and how antibodies contribute to these cellular immune responses.
• Covers the histochemistry of macrophage activation; the roles of various cytokines; the effects of glucocorticoids, estrogens, thyroid…