DNA Recombination

Homologous recombination involves the precise exchange of similar or identical nucleic acid sequences between two DNA molecules. This process directs the repair of many DNA lesions in somatic cells and generates genetic variation in sperm and egg cells during meiosis. It is a nearly universal biological process that is conserved from phage to humans.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers all aspects of re…