Dendritic Cells in Cancer

It is now known that the suppression and redirection of the immune response, which allows for tumor development and growth in the previously immune-competent host, are significant features of cancer. Dendritic cells are central to the development of immune responses and not surprisingly these cells are strongly impacted by tumors and factors derived from them, as well as by other conditions associated with tumor progression and cancer treatments. Further, as some of the frontline strategies f…