Actin-Binding Proteins and Disease

This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin _4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a cha…